The kidney is considered a major homeostatic organ because it maintains the balance of water, ions, and electrolytes in the blood.
Kidneys extract wastes and excess fluid from the body, kidneys also remove acid that is created by the cells in the body and sustain a healthy equilibrium of salts, water, and minerals like sodium, potassium, calcium, and phosphorus in the blood.
Each kidney consists of almost a million filtering units called nephrons. Every nephron has a filter, called the tubule, and a glomerulus. The nephrons function via a two-step process, the glomerulus purifies the blood, and the tubule returns required substances to the blood and clears wastes.
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A frame shift mutation is the shift of the genetics of an object.
This type of mutation os caused by the insertion or deletion of nucleotides in a DNA sequence that is not divisible by three.