Sodium
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Past climate changes led to extinction of many species, population migrations, and pronounced changes in the land surface and ocean circulation. The speed of the current climate change is faster than most of the past events, making it more difficult for human societies and the natural world to adapt.
An animal can respond in negative ways such as: biting, scratching, urinating, whining, restlessness, snippy, or getting sick.
C. Genetic variation
Bacteria are very numerous, and random mutation of bacterial DNA generates a wide variety of change, including resistance. It happens through mutation and selection. Not only are they capable of sharing genetic bits of DNA to related and unrealted species they can develop ways to remove the antibiotic before it reaches its intended area via biochemical pumps or enzymes to inactiavte the antibiotic.
