Adenylate cyclases (ACs) are the membrane-bound glycoproteins that convert ATP to cAMP and pyrophosphate.
When activated by G-protein Gs, adenylate cyclases (ACs), which are membrane-bound glycoproteins, catalyze the synthesis of cAMP from ATP.
Different AC isoforms are widely expressed in various tissues that participate in regulatory systems in response to particular stimuli.
Humans have 9 different AC isoforms, with AC5 and AC6 thought to be particularly important for cardiac activities.
Nitric oxide has an impact on the activity of AC6, hence the protein's nitrosylation may control how it works. However, little is known about the structural variables that affect nitrosylation in ACs and how they relate to G's.
We predict the cysteines that are prone to nitrosylation using this 3D model, and we use virtual ligand screening to find potential new AC6 ligands.
According to our model, the AC-Gs interface's Cys174 in G's and Cys1004 in AC6 (subunit C2) are two potential residues that could experience reversible nitrosylation.
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Bonds.
Guaranteeing savers high rates of return.
<h3>What is the purpose of the financial system?</h3>
- A financial system performs the role of an intermediary and makes it easier for money to move from areas of surplus to areas of deficit. It comprises various institutions, markets, rules and laws, customs, investors, analysts, transactions, and claims and liabilities.
- Managers can use big data in their businesses by using a financial system. A financial system combines data from numerous organizational departments into a single perspective, making it simple for users to comprehend the connections between distinct data types.
- Financial services guarantee the advancement of both domestic and international trade. Increased domestic and international exports of goods are guaranteed by the presence of factoring and forfeiting businesses. Banking and insurance services also facilitate an increase in these promotional activities.
The following are financial securities that represent promises to repay a fixed amount of funds: Bonds.
- Bonds provide a fixed amount of maturity value.
The following is not a service that the financial system provides for savers and borrowers: Guaranteeing savers high rates of return.
- The financial market can't guarantee any particular rate of return to savers.
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<span>C. A greater number of wavelengths pass a given point per second.
hope this helps
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Option C:
B. wild-type 5-AUGCAUACAUUGGAGUGA-3 mutant 5'-AUGCAUACAUCUGGAGUGA- 3'
Explanation:
A frameshift mutation is a genetic mutation such that the triplet nature of gene expression by codons, the insertion or deletion occurs in such as way that it alters the complete sequence of 3 codon sets and can change the reading frame, resulting in a completely different translation from the original.
As it is pertinent to understanding that all genes are normally translated in sets of 3 codons, which typically describes and explain a unique amino acid sequence. Thus, if a frame shift mutation occurs, it can affect many amino acid sequences and finally the entire protein.
If we look at option B:
wild-type 5-AUG CAU ACA UUG GAG UGA-3
mutant 5’- AUG CAU ACA UCU GGA GUG A-3’
An insertion of a base Uracil showed at the end of 3rd codon which affected and altered the whole sequence of codon triplets. This changed all next codons and finally all next amino acids will be altered.
