This is called a frameshift mutation....
Losing one nucleotide would cause the entire framework of codons (the 3 nucleotide set that codes for the amino acids) to move off by 1 which results in likely completely different amino acids being called for when the protein is built.
In the case of CF, the normal CFTR gene which codes for Cystic Fibrosis Transmembrane Receptor - a membrane protein, with a point mutation would not be made properly and is therefore not placed into the membrane of the cells of the offspring - this protein is very important in moving sodium into the cell - if this is messed up it results in disease.
Note that CF can result in a number of different types of mutations to the CFTR gene...a frameshift mutation is just one way.
Every cell of the body contains the same DNA. So, the nerve cells and the blood cells have the same set of genetic instructions.
Different cells are produced by differential use of that DNA. Different sets of genes must be turned on and off in the various cell types (differently expressed genes).
Most cells in a human body contain a complete set of the genome <span>( the genetic material of an organism), which is two sets of 23 chromosomes, with exception of egg and sperm cells, which carry only half a set of chromosomes (23 instead of 46).</span>
<span>Steel that is strong but cheap could be used for bridges and skyscrapers because for something needed to be so dependable,it would of had to go through extensive quality control. And the steel producer would have to prove it can hold up and explain why it's cheap.</span>