Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Answer:
"Genetic makeup" is the appropriate choice.
Explanation:
- The phrase "Genetic makeup" refers to something like the factors that regulate how much those who look with as well as what physicochemical traits visitors possess.
- They seem to be someone's genotype, but once those genetic mutations have been demonstrated, you illustrate or highlight your phenotype.
Proteins are made of hundreds and thousands of polymers called Amino Acid which are attached with each other in long chains. There are 20 different types of amino acids that make up a protein
A. Your leg jumping when it is hit by a reflex hammer
