The best answer would be the third option. Extended joints is a possible result of low levels of activity caused by being overweight. Being overweight, adds more pressure on your body parts which could lead to diseases that involve the joints. The most common is arthritis. More weight means more pressure on our joints especially on the lower part of the body.
True is the answer
Incorrect use of drugs could cause an overdose, which could eventually lead to death
Incorrect use of dietary supplements ( lets say you take different type of supplements without knowing what you're doing) , could create a toxic result for your body, which also could eventually lead to death
I think one of them is B I’m not sure for the other
D. Large intestines
Hope this helps :)