somatic hypermutation occurs only in the <u>V or Variable</u> regions of rearranged heavy and light chains.
Somatic hypermutation occurs only in activated B cells, not T cells. This occurs in germinal establishments inside of lymph nodes and the spleen, where B cells are stimulated and T cells are present. Somatic hypermutation is a procedure in which point mutations pile up at rates 106-fold greater than the background mutation rates observed in other genes in the antibody V-regions of both the light and heavy chains.
Somatic hypermutation of immunoglobulin (Ig) genes is important in antibody-mediated immunity. SHM in B cells serves as the molecular foundation for antibody affinity maturation. In this way, SHM plays an important role in optimizing antibody-dependent immune responses.
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Answer:the radiation of the Sun’s electromagnetic waves
Explanation:
Answer:
The ratio of blue to white offspring in the progeny is 4 blue : 12 white.
Explanation:
<u>Available data:</u>
- The dominant allele K is necessary to synthesize blue flower pigment
- K is inhibited by the dominant allele D
- Plants with the genotype K- D- will not produce pigment (and their flowers will be white)
Cross: testcross for (Kk Dd) plants
Parental) KkDd x kkdd
Gametes) KD kD Kd kd
kd kd kd kd
Punnet square) KD Kd kD kd
kd KkDd Kkdd kkDd kkdd
kd KkDd Kkdd kkDd kkdd
kd KkDd Kkdd kkDd kkdd
kd KkDd Kkdd kkDd kkdd
- Whenever D is present, it inhibits the expression of the K gene, so every plant with the dominant D allele will be white. This plants´ genotype is kkD- or K-D-.
- Whenever D is absent and K is present, every plant with genotype K-dd will be blue.
- The recessive form for K and D genes will express white-flowered plants, with genotype ddkk
F1) Progeny genotype: 4/16 KkDd, white-flowered plants
4/16 Kkdd, blue-flowered plants
4/16 kkDd, white-flowered plants
4/16 kkdd, white-flowered plants
The ratio of blue to white offspring in the progeny is 4 blue : 12 white.
Blue-flowered plants: 4 Kkdd
White-flowered plants: 4 KkDd + 4 kkDd + 4 kkdd
Species is a type or kind of thing while ecomorph is a local variety of a species whose appearance is determined by it's ecological environment
It is necessary to calibrate the ocular micrometer with each objective because the magnification of each objective lens are different. The numerical value is specific and only holds for a specific objective ocular lens. So, they should be checked accordingly.