A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site is the instructors best response.
Explanation:
Receptors are Macromolecules which involved in chemical signalling within cells. It is possible that receptors are located in the cell surface membrane. Cellular biochemical process is regulated by Activated receptor. The drugs are capable to affect to receptor who is related to the drug’s affinity and also intrinsic efficacy.
The affinity and activity of drug is related to its chemical structure. its effect is decided by the time duration where complex persistence of drug-receptor.
<u>Answer:</u>
Effects Include:
Activates secondary messengers such as cAMP which further activates number of hormones like
- ADH: production of this hormone causes kidneys to retain more water inside body.
- GHRH: release growth factors and stimulates growth of organism.
- ACTH: produces fight or flight responses i.e rise in heart beat, rise in Blood pressure etc
- TSH: Stimulate the synthesis of Thyroid hormone and enhances the metabolism of body. In rare cases causes Goiter without the deficiency of Iodine.
- LH: Stimulate follicle maturation and formation of ovules in women.
- Calcitonin: Decreases blood calcium level by deposition calcium in bones. This effect weakens the muscles.
- Glucagon: Stimulates glycogen breakdown from liver and muscles and many more effects.
<u>Explanation:</u>
Background Knowledge:
GPCR (G Protien coupled receptors) are present inside plasma membrane in huge amount. As name suggest that these receptors are coupled with G proteins during their inactive state present inside of the cell. During their Inactive state these G proteins are bounded with GDP molecule.
Upon receiving signal molecules from outside of cell alters the shape of GPCR. These receptors also triggers change in G Protein, as a result of this GTP get attached with them. This protein further activates reaction cascades inside of the cell.
What happen if GTP cannot be hydrolyzed to GDP + Pi?
If GTP cannot hydrolyzed in to GDP + Pi than, it cannot be able to dissociate from G proteins. Cascade system doesn't stop and produces many effects on body.
Effects Include:
Activates secondary messengers such as cAMP which further activates number of hormones like
- ADH: production of this hormone causes kidneys to retain more water inside body.
- GHRH: release growth factors and stimulates growth of organism.
- ACTH: produces fight or flight responses i.e rise in heart beat, rise in Blood pressure etc
- TSH: Stimulate the synthesis of Thyroid hormone and enhances the metabolism of body. In rare cases causes Goiter without the deficiency of Iodine.
- LH: Stimulate follicle maturation and formation of ovules in women.
- Calcitonin: Decreases blood calcium level by deposition calcium in bones. This effect weakens the muscles.
- Glucagon: Stimulates glycogen breakdown from liver and muscles and many more effects.
Answer:
The graph shows that the population of bacteria is increasing with the passage of time. During 1st hour, the population of bacteria is 50 per ml. In second hour, the population is doubled i. e. 100 per ml. In the 3rd hour, the population reaches to 200 per ml and in 3 and half hours, the population touches the value of 300 per ml. So the graph clearly shows that population is double with each hour.
Yes ..................................
