Answer:
Cystic fibrosis (CF) is more common in Caucasian individuals and is inherited with an autosomal recessive inheritance pattern.
Explanation:
Cystic fibrosis (CF) is a condition of genetic origin, which affects organs such as the lungs, pancreas, intestine and liver. CF is characterized by the production of very thick and viscous mucus, and promotes the formation of cysts and fibrosis of the affected organs.
CF is an inherited disease that is transmitted in an autosomal recessive pattern, that is, the altered gene is required to be on both chromosomes of the allelic pair, in order to be expressed.
It is a very common disease in Caucasian individuals, especially those of European descent.
Ans.
HD (Huntington's disease) is a genetic neurological disorder that occurs due to damage and death of brain cells. it is caused by an autosomal dominant mutation in HTT (huntingtin) gene, having a trinucleotide repeat section that makes HTT protein.
The mutation leads to an increase in this nucleotide repeat count, associated with formation of altered or mutated huntingtin protein. These altered proteins show deleterious affect on brain cells and result in Huntington's disease.
Thus, the correct answer is 'option A). a mutated gene.'
Answer:
proteins are only able to function properly in their specific shape, they will typically stay in that configuration unless something forces them to change. When proteins change their shape, this is called denaturation. Some external forces that affect protein shape are pH and temperature
Answer:
C) binding to mRNAs and degrading them or blocking their translation
Explanation:
<u>miRNAs:</u>
miRNAs is the abbreviation of MicroRNAs. These are the small noncoding RNAs of ∼22 nucleotides which can not code for peptides. miRNAs are responsible for gene expression regulation at the level of post transcription. They can do so by forming complementary base pairing with target mRNA and inhibiting their translation.
They silenced mRNA by the following processes:
(1) Cleavage of the mRNA strand into pieces,
(2) stopping mRNA from translation into proteins by ribosomes.
(3) Shortening of mRNA poly(A) tail and destabilizing it.
