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European rabbits (Oryctolagus cuniculus) were introduced to Australia in the 18th century with the First Fleet and eventually became widespread. Such wild rabbit populations are a serious mammalian pest and invasive species in Australia causing millions of dollars of damage to crops.
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West Nile virus (WNV) causes epidemics of febrile illness, meningitis, encephalitis, and flaccid paralysis. Since it was first detected in New York City in 1999, and through 2004, 16,000 WNV disease cases have been reported in the United States. Over the past 5 years, research on WNV disease has expanded rapidly. This review highlights new information regarding the virology, clinical manifestations, and pathology of WNV disease, which will provide a new platform for further research into diagnosis, treatment, and possible prevention of WNV through vaccination.
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