Why might you expect fluorocitrate to have an inhibitory effect on one or more of the TCA cycle enzymes if incubated with the pu

Question

liberstina [14]

3 years ago

12

Why might you expect fluorocitrate to have an inhibitory effect on one or more of the TCA cycle enzymes if incubated with the pu

rified enzymes in vitro, even though fluoroacetate has no effect?

Biology

1 answer:

dezoksy [38] · Answer 1 · 2022-06-27T15:38:28+03:00

dezoksy [38]3 years ago

3 0

Answer:

This is because tricarboxylic acid (TCA) cycle is central to cellular energy production in the mitochondria of higher organisms and fluoroacetate interrupts the TCA cycle.