What is responsible for termination of transcription in eukaryotic protein-coding genes?

Biology

1 answer:

kupik [55]3 years ago

7 0

Answer:

<h2>A polyadenylation signal or poly(A) </h2>

Explanation:

Termination. In eukaryotes, transcription is terminated differently for the all 3 different RNA polymerases. Transcription is terminated by two elements: i) a poly(A) signal and ii) a downstream terminator sequence.

In eukaryotic protein-encoding genes, the cleavage site in the RNA occurs between an upstream( the sequence before the cleavage site) AAUAAA and a downstream GU-rich, separated by approx 40-60 nucleotides. After they both have been transcribed, a protein knows as CPSF and another protein called CstF( in humans) helps in termination.

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