The statements that are true are the following:
1. The levels of microsomal enzymes are decreased.
Microsomal enzymes are functional parts of the human liver, which participate actively in the drug metabolism. It has been shown that the activity of these enzymes is lower in children, reaching its full activity in adult individuals.
2. First pass elimination is reduced because of the immaturity of the liver.
First pass elimination is a phenomenon of drug metabolism, that occurs in the liver or the gut and involves the reduction of the drug concentration before it reaches the systemic circulation. In neonates, the liver is immature and undergoes several changes during the postnatal period.
3. Gastric emptying is slowed because of slow or irregular peristalsis.
Peristalsis is a term referring to the movement of food to several positions of the digestive tract, through muscle contractions. Gastric emptying is strongly affected by peristalsis. Some children have irregular peristaltic movement.
In a deep wound, there might be a few layers of tissue that need to be rebuilt because they were lost. In this rebuilding process this pebbly texture can be seen and it indicates that granulation is taking place (that's the process). Granulation is when small blood vessels and capillaries start to develop vertically to the outside part of the wound, being supported by connective tissue, and surrounded by cells of many other types for different purposes, such as immunitary functions or specialised tissue functions. This tissue growing is characteristic of healing and it presents this granulated/pebbly texture to it.
Osmosis<span> is the phenomenon of the movement of Solvent molecules from lower solute conc. to higher solute conc. through a semi-permeable membrane to make solute conc. equal on both sides.</span>
