MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
The cell cycle ensures the duplication of the genome and its distribution in daughter cells by passing through a coordinated and regulated sequence of events.
A series of checkpoints guarantee the orderly progression of the phases of cell division and the correct distribution of the duplicated genetic material in the daughter cells.
The checkpoints during mitosis are:
- At the end of stage G1 and before S.
- Before anaphase in mitosis.
- DNA damage checkpoints in G1, S or G2.
The checkpoint before anaphase in mitosis guarantees the separation of chromosomes, and operates by activating the Mad2 protein that prevents the degradation of segurin, until the conditions are appropriate.
That is, the Mad2 protein prevents the segregation of sister chromatids until they have all bound to the spindle.
Therefore, we can conclude that MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
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A vascular plant is a plant that is characterized by the presence of conducting tissue.
The asthenosphere lies 80-200km below the surface under the lithosphere. Convection also occurs in the asthenosphere. The asthenosphere is mostly made of up rock material (magnesium and iron silicates). The asthenosphere makes up 6% of the mantle and lets the lithosphere move.
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Special properties of an oxygen-binding protein in the muscles of marine mammals, such as seals, whales and dolphins, are the reason these animals can hold their breath underwater for long periods of time, according to a new study. ... In fact, the amount was so high in the muscle that it almost looked black in color.
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Answer: A, B, and D
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