Answer:
The correct answer is The cells do not have proper receptor.
Explanation:
During paracrine signaling a signaling molecules are generated from one cell.The generated signaling molecule then binds to the receptor of neighboring cell to carry specific signal from donor cell to the acceptor cell.
But the signaling molecules will not bind to the cell that is producing it because that producing cell do not contain proper receptor to bind that signaling molecule.
The binding of signaling molecule to the receptor of its producing cell occur during autocrine signaling.
Answer:
Binding of <u>ACh (acetylcholine) </u> to receptors (ligand-gated) on the sarcolemma at the neuromuscular junction is vital for depolarization of the muscle fiber.
Explanation:
It allows acetylcholine to be released into this synapse when an action potential hits a neuromuscular junction. Acetylcholine attaches to the nicotinic receptors localized on the post-synaptic membrane of the muscle fibre's motor end plate, a specialized region.
Hence , the answer is <u>ACh (acetylcholine) .</u>