Question

Binding of ________________ to receptors (ligand-gated) on the sarcolemma at the neuromuscular junction is vital for depolarization of the muscle fiber.

Answer 1

Answer:

Binding of   ACh (acetylcholine)    to receptors (ligand-gated) on the sarcolemma at the neuromuscular junction is vital for depolarization of the muscle fiber.

Explanation:

It allows acetylcholine to be released into this synapse when an action potential hits a neuromuscular junction. Acetylcholine attaches to the nicotinic receptors localized on the post-synaptic membrane of the muscle fibre's motor end plate, a specialized region.

Hence , the answer is  ACh (acetylcholine) .