You start with what's in the brackets (which are the same as parenthesis). There's no symbol between the two parentheses, therefore you multiply them together. Since it contains both multiplication and subtraction, using PEMDAS, you would do multiplication first.
-3 x 2 = -6 since a negative times a positive equals a negative.
Next, you subtract 4 from -6.
4 - (-6) = -10 since subtracting two negatives is basically addition.
Now, you're left with -5(-10). All you have to do is multiply.
-5 x (-10) = -50 since a negative times a negative equals a positive.
