Helicase's primary function is to separate the annealed nucleic acid strands. It is a motor protein and moves directionally along the phosphodiester backbone. It usually separates strands of double helix DNA or self annealed RNA. It used the energy from ATP hydrolysis and breaks hydrogen bonds between nucleotide bases.
In human body 95 types of helicases are found. They have sequence motifs required for ATP binding, ATP hydrolysis and translocation along nucleic acid phosphodiester backbone. The variable portion in their amino acid sequence imparts specific feature to each helicase.
telophase || begins after the separation of sister, chromatids in this phase individual chromosomes reach at pole nuclear membrane starts getting formed around them and cytokinesis take place cytokinesis is the division of cytoplasm this result in the formation of four daughter cell which are haploid.
