Chimeric mice are generated where approximately 50% of the cells in the animal are genetically MHC class I-deficient. The other 50% are deficient for the herpes virus receptor, HVEM, but do express MHC class I molecules. When these mice are infected with herpesvirus by intraperitoneal injection, a robust virus-specific CD8 T cell response is detected at day 7 post-infection in the spleens of the infected mice.
Chimeric mice are generated where approximately 50% of the cells in the animal are genetically MHC class I-deficient - Immunobiology
: a branch of biology concerned with the physiological reactions characteristic of the immune state
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The awnser is b there is a mutation in the gene
<span>vestigial structures because they are hard </span>
Answer:
Thymine in DNA occurs as the result of thymidylate synthase creating deoxythymidine monophosphate (dTMP), which then undergoes phosphorylation to deoxythymidine diphosphate (dTDP), then to Deoxythymidine triphosphate (dTTP), and incorporated into DNA by the DNA polymerase (DNA pol). Thymine in tRNA arises post-transcriptionally, by S-adenosylmethionine-dependent methylation of a uridine 5'-monophosphate (UMP) residue in RNA.
Explanation:
Thymidylate synthase is an enzyme involved in <em>de novo</em> DNA synthesis. This enzyme (thymidylate synthase) catalyzes the transfer of the one-carbon group from 5,10-methylene-tetrahydrofolate (5,10-CH2-THF) to deoxyuridine monophosphate (dUMP) and subsequent methylation to produce deoxythymidine monophosphate (dTMP), which is then phosphorylated to deoxythymidine triphosphate (dTTP) by kinases and incorporated into DNA. On the other hand, specific tRNA methylases catalyze the methylation of transference RNA (tRNA) by using S-adenosylmethionine as a methyl donor. Since tRNA methylation is a post-transcriptional modification, this chemical reaction is considered an epitranscriptomic modification on the RNA molecule.
Answer:
translation
Explanation:
Translation takes place at a ribosome in the cytoplasm. During translation, the genetic code in mRNA is read to make a protein.
