1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
emmasim [6.3K]
2 years ago
15

Scurvy is a disease that until the nineteenth century was common among sailors and others whose diets were deficient in vitamin

C (ascorbic acid). Individuals with scurvy suffer from various disorders, including extensive bruising, hemorrhages, and breakdown of supporting tissues. Ascorbic acid serves as a reducing agent responsible for maintaining the activity of prolyl hydroxylase, the enzyme that catalyzes hydroxylation of proline residues within the collagen triple helix, which is required for helix stability.
(a) Based on this information, postulate a role for hydroxyproline in collagen triple helices, and explain the sequence of events leading from a dietary vitamin C deficiency to symptoms such as bruising and breakdown of supporting tissues.
(b) Can you guess why sailors are no longer susceptible to scurvy? Why are British sailors called "limeys" to this day?
Biology
1 answer:
alina1380 [7]2 years ago
5 0
<h2>Scurvy </h2>

Explanation:

(a) Collagen is the major structural component of cartilage,bones and tendons

  • The basic unit of collagen is tropocollagen and each tropocollagen consists of three coiled left handed polypeptide chains called α chains
  • Generally each α chain consists of a repeating tripeptide sequence called: G-X-Y
  • Here G represents glycine; X represents proline and Y represents hydroxyproline
  • Rigidity of collagen molecule is due to presence of proline and hydroxyproline
  • Hydroxylation of proline is catalysed by prolyl hydroxylase enzyme which use ascorbate,α ketoglutarate and oxygen
  • α ketoglutarate is oxidatively decarboxylated to form carbon dioxide and succinate
  • Sequence of events leading from a dietary vitamin C deficiency to symptoms such as bruising and breakdown of supporting tissues includes: tissue levels of ascorbic acid is low;  enzyme prolyl hydroxylase is inactive;  proline is not hydroxylated;  the triple helix is inadequately stabilized; collagen breaks down;  defects in tissues that depend on collagen ; tissues that depend on collagen are subject to breakdown and bruising

(b) Sailors are no longer susceptible to scurvy because fresh fruits which are the source of vitamin C source are available now

British sailors called "limeys" to this day,this term reflects the British navy's use of limes

You might be interested in
Which of the following blood vessels are small, thin, and porous enough to exchange substances at the tissue level of organizati
Dafna1 [17]

Answer: The correct answer is capillaries

Explanation:

capillaries are tiny branched blood vessels that links arterioles to venules and allows exchange of nutrients and gases between the blood and its surrounding tissues

6 0
3 years ago
Explain your justification for the changes in trait distribution between years 1 and 10. What do you think will happen to the po
Katen [24]

Answer:

I need an imago or a graph

Explanation:

3 0
3 years ago
Tissue found in leaf stalks below the epidermis is________.
NISA [10]
<h2 /><h2><em><u>Collenchyma</u></em><em><u>.</u></em></h2>

<em><u>Explaination</u></em>

<em><u>Collenchyma is the tissue found below the epidermis of a leaf stalk. These are simple permanent tissue, perform photosynthesis when chloroplast is present</u></em><em><u>.</u></em>

5 0
3 years ago
Read 2 more answers
Why do you think Community Health Workers serve as connectors to the community?​
olga2289 [7]

Answer:

CHWs may perform the following roles: Create connections between vulnerable populations and healthcare providers. ... Ensure cultural competence among healthcare providers serving vulnerable populations. Educate healthcare providers and stakeholders about community health needs

Explanation:

Hope it helps! Correct me if I am wrong!

I'm sure about my answer!

If you dont mind can you please mark me as brainlest?

Its ok if you don't want to!

8 0
3 years ago
Which of the following is an example of a decomposer?
kakasveta [241]
Mushroom......A decomposer is something that can be broken down
8 0
2 years ago
Read 2 more answers
Other questions:
  • Which nonforfeiture option provides coverage for the longest period of time?
    12·1 answer
  • An Olympic sprinter readies for a race. After the sound of the starting gun, he propels himself forward from the starting block
    9·1 answer
  • Looking into your microscope, you spot an unusual cell. Instead of the typical rounded cell shape, the cell has a very narrow mi
    13·1 answer
  • Multicellular organisms have some advantages over single-celled organisms, but there are also disadvantages of being multicellua
    13·1 answer
  • Which of the following could be a description of the cytoskeleton in a cell? scaffolding water hose drawbridge of jelly
    10·1 answer
  • What are the three parts of the light dependent reactions
    11·1 answer
  • Duchenne muscular dystrophy is a genetic disorder that arises from a recessive X-linked allele. Why is this disorder almost alwa
    15·2 answers
  • "tertiary structure of a protein is maintained by (list the interactions)"
    9·1 answer
  • During mitosis, the original cell produces two daughter cells. How many daughter cells will be produced if 250 mouse cells under
    12·1 answer
  • The unweathered parenental rock is also known as​
    14·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!