<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
<span>A diseases may be classified as either communicable or non-communicable. Communicable diseases are caused by pathogens who inhabit a host, man (I'm not saying man is the only host or man is necessarily the final host; there could be many host) who in turn passes the disease to another. Pathogens are viral, bacterial, parasitic and fungal. There are several stages before the pathogen metamorphoses into a full-blown disease. The stages in which several events happen builds up before the pathogen affects the final host is called a communicable disease chain. There are six stages ( Pathogen, reservoir, portal of ext, mode of transmission, portal of entry and susceptible host) in the communicable disease chain but the step a nurse shouod take is
1. Destroy the second link (Reservoir) by thoroughly sanitizing the environment. Obviously, this is where the Pathogens live. If the reservoir is taken care of; there's no way they could infect the host.</span>
Answer:
The correct answer will be- proteoglycans and the glycoproteins
Explanation:
The connective tissue forms a very large proportion of the total mass of a body. The connective tissue plays a distinct role in the body like the movement of the cell, mechanical support, wound healing but the main role is to connect different tissues of the body.
The property of the connective tissue is determined by the amount and type of the extracellular matrix present which contains three main components which are the fibres like collagen, glycoproteins and the proteoglycans.
Thus, proteoglycans and glycoproteins are the correct options.
