1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
aliya0001 [1]
2 years ago
6

A mutation in a G-protein prevents the alpha-subunit from dissociating from the beta/gamma-subunit. What effect will this have o

n the pathway in which the G-protein is involved?
Biology
1 answer:
Ymorist [56]2 years ago
8 0

Answer:

the pathway will be under-expressed.

  • the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
  • when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.

if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.  

The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.

G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.

As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.

You might be interested in
Evesa
Artist 52 [7]

Answer:

Active uptake (which I think you mean active transport) is important when the concentration gradient is against that of a certain substance, so it doesn't cross the membrane through diffusion or passive transport. It is sometimes necessary if a substance needs to move across a membrane but can't do so due to electrical charge or that there is a substance on the other side of the membrane preventing diffusion.

Explanation:

8 0
3 years ago
The synaptic knob releases acetylcholine into the synaptic cleft, which is received by receptors on the motor end plate. which s
wlad13 [49]
It portrays the neuromuscular junction of a skeletal muscle. 
The breakdown items are consumed by the pre-synaptic neuron by endocytosis and used to re-combine more neurotransmitter, utilizing vitality from the mitochondria. The Cytoplasm in the Synaptic Knob has a high extent of specific organelles. These incorporate smooth endoplasmic reticulum, mitochondria, and vesicles.
4 0
2 years ago
What was the environment in early earth would we have been able to survive it? Why or why not
Art [367]

Answer:

Without an oxygen atmosphere very few things could live on the early Earth. Anaerobic bacteria were probably the first living things on Earth. The early Earth had no oceans and was frequently hit with meteorites and asteroids.

Explanation:

4 0
3 years ago
What macromolecule is the most common in the item in the picture?
Rama09 [41]

Answer:

If that is a picture of DNA, then nucleic acids are the most common macromolecule

Explanation:

5 0
2 years ago
Which of the following is the critical function of proteins?
Svetllana [295]

Answer:

A critical function of proteins is their activity as enzymes, which are needed to catalyze almost all biological reactions.

5 0
3 years ago
Other questions:
  • Some molecules are too big to pass through the phospholipid bilayer of the cell membrane. These molecules need to pass through _
    7·2 answers
  • Consider the roles of valves and blood vessel walls in moving blood through the body. If you were given a piece of flexible tubi
    7·1 answer
  • In what water temperature do sharks swimin?
    8·1 answer
  • Biodiversity can be studied at which of three levels?
    13·2 answers
  • Why is the frequency of X–linked disorders greater in males compared to females?
    6·2 answers
  • Which statement correctly identifies a difference in the structure of proteins and polysaccharides
    8·1 answer
  • The Krebs cycle forms many products. Which option lists the correct products of the Krebs cycle after 1 molecule of glucose goes
    7·1 answer
  • Analyze the graph showing the rate of photosynthesis activity as a function of carbon dioxide levels. Select as many of the choi
    12·2 answers
  • What does not require energy
    5·1 answer
  • What are the two major methods by which cells communicate to coordinate their functions?.
    11·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!