Single-cell RNA-sequencing (scRNA-seq) provides the chance to analyze heterogeneous cellular compositions and probe the patterns of gene expression that are unique to each cell type under various circumstances. However, batch effects like lab setups and individual variability make it difficult to use them in cross-condition designs.
<h3>What is Single-cell transcriptomes ?</h3>
In single-cell transcriptomics, the messenger RNA levels of hundreds to thousands of genes are simultaneously measured to assess the degree of gene expression in individual cells within a particular population.
<h3>Advantages : </h3>
• Integrated protocol proceeds directly from whole cells and preserves sample integrity.
• High resolution analysis enables discovery of cellular differences typically hidden by bulk sampling methods.
• Robust transcriptome analysis down to single-cell input levels for high-quality samples.
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The most distinctive feature of ape dentition, which clearly distinguishes apes from Old World monkeys, is a Y-5 molar pattern.
<h3>What is the Y-5 molar pattern?</h3>
- This is a distinctive type of molar teeth pattern found in apes and hominoids.
- In this, 5 cusps or raised surfaces are present on the grinding surface of teeth, roughly forming a Y- shape. Therefore, this is also known as Y-5 pattern.
- Whereas Old world monkeys have only 4 cusps on their lower molars present in a bilophodont pattern.
- A Y-5 molar is formed when the tooth is divided into different pieces which form the complete structure of the tooth.
- In bilophodont pattern the tooth is divided into 2 symmetric sections.
- The dental formula of apes is 2.1.2.3/2.1.2.3 i.e. 2 incisors, 1 canine, 2 premolars, 3 molars.
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It's either the Pacific ocean or El niño
hope this helps somehow
Because it’s more likely that chance events will significantly change the frequencies of alleles in the population
The creation of DNA fragments with ends that can join with other DNA is achieved by the use of restrictive enzyme analysis.
<h3>What are restriction enzymes?</h3>
They are enzymes utilized in genetic engineering or gene recombination technology to cut DNA at some specific points in other to have sticky ends.
The sticky ends DNAs are able to join with other DNAs using these ends. Another enzyme (Ligase) is utilized to join the DNA back once the desired DNA has been inculcated.
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