Question

Complete the sentences to correctly describe steps in fatty acid synthesis. move the terms to the appropriate blanks. some terms will not be used, and some will be used more than once. scroll down to see all the terms. note that a single red x will appear if you answer any of the blanks incorrectly. feedback will be placed next to a blank that is incorrectly filled. fatty acid synthesis begins with a preparatory step in which is transferred from to the . however, it cannot pass through the membrane, so it is transported as , which is cleaved to and . in the cytosol, acetyl coa is converted to , a three-carbon compound. fatty acid synthesis begins with the transfer of the acetyl group from acetyl coa to fatty acid synthase. -carbon groups, supplied by , are added to the growing acyl chain in a series of steps involving condensation, , and dehydration reactions. elongation of the fatty acid chain stops at carbon atoms, after cycles, as the free fatty acid is released.

Answer 1

The synthesis of fatty acids starts with a preparatory step in which acetyl-CoA is mediated from mitochondria to the cytosol. However, it cannot pass through the membrane, so it is transported as citrate, which is cleaved to acetyl CoA and oxaloacetate.

In the cytosol, acetyl CoA is transformed to malonyl CoA, that is, a three carbon compound. Fatty acid synthesis starts with the conduction of acetyl group from acetyl CoA to fatty acid synthase.

Two carbon groups, supplied to malonyl CoA, are supplemented to the developing acyl chain in a series of steps involving condensation, reduction, and dehydration reactions. Elongation of the fatty acid chain ceases at 16 carbon atoms, after seven cycles, as the free free fatty acid is discharged.