<h2>b) option is correct </h2>
Explanation:
- Some bacterial toxins cause disease by altering the activity of G protein, cholera toxin is one of them
- Cholera toxin catalyse ADP ribosylation of Gs and blocks GTPase activity thus Gs GTP become permanently active
- Constitutive activation of Gs protein continuously induce adenylyl cyclase, cytosolic cAMP level rises that leads to activation of protein kinase A (pKA)
- Activated pKA catalyse phosphorylation of two transmembrane proteins of intestinal epithelial cells:
- CFTR cause excessive outflow of Cl- ion and Na+ H+ exchange cause efflux of Na+ ion, both enters in gut and form Na+ Cl-
- Na+Cl- leads to outflow of water from the gut, resulting in diarrhea and dehydration and this condition may cause death of organisms due to loss of water and ions
1. The trade winds
2. The Coriolis Effect, in combination with an area of high pressure, causes the prevailing winds—the trade winds—to move from east to west on both sides of the equator across this 60-degree "belt." ... The sinking air triggers the calm trade winds and little precipitation, completing the cycle
3.north south direction
Scientific methods must be supported by observations and results from many investigations and are not absolute.
Answer:
The ovules would develop into a seed after fertilisation. #4 is pointing to it
It begins with the unzipping of the double helix by
helicases. Unzipping forms y-shaped replication forks
exposing promoter regions (TATA regions) where the initiator proteins and factor bind to
the regions of DNA. A primer also
attaches to the region. DNA polymerase then
binds to the regions and begins adding DNA nucleotides
to the 3’ end of the primer based on the nucleotides on the template strand. Topoisomerase continues to unwind the DNA as the
polymerase progresses to the end of
replication.