The flow of energy from the Earth's interior originates from two main sources: the radiogenic and primordial heat respectively. Radiogenic heat is produced by the radioactive decay of isotopes in the mantle, whereas primordial heat is the energy left over since the Earth's formation.
Without using any sensitive scientific equipment, this flow of energy is observable at stress points between the tectonic plates, such as volcanoes. These are ruptures in the crust of the planet through which materials from the interior of the planet are expelled.
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DNA synthesis occurs during the S phase, between the G1 and G2 phases of interphase. DNA replication is therefore complete before the mitotic phase begins.
Disruption in protein homeostasis leads to the appearance and accumulation of intermediate nonnative conformations that tend to form oligomeric and aggregated species, which over time cause cellular injury..
Given that an average human has a heart rate of 70 beats per minute and if one is to have a 70 year life span, the number of times it will beat is 2,575,440,000 times. This was computed by multiply 70 years by 365 days/year x 24 hours/day x 60 minutes/hour x 70 beats/min. Thus, the heart will beat numerous times before it finally stops.