Positioning. Multiple positions may be used to accomplish a digital rectal examination. The easiest for the examiner is to have the patient tuck the knees up to the chest, either in the dorsal lithotomy position or the lateral recumbent position.
Answer:
There is a low probability that a future pregnancy would exhibit similar phenotypes since it probably was a germinative line mutation that affected that egg.
Explanation:
The malformations of the unborn child, probably are due to a mutation in the germ cell of any or both parents. Germline mutations are detectable changes in a sperm or egg that we can see when the fetus is growing, as malformations since the original germ cell that was mutated divided itself to give more mutated cells for all the different parts of the fetus.
Answer:
The white blood cells i.e. granulocytes and macrophages are specifically stimulated by GM-CSF in response to chemotherapy in cancer patients.
Explanation:
The colony stimulating factors (CSFs) are the regulators of granulocytes and macrophages in blood. The CSFs has the potential to regenerate the white blood cells damaged during chemotherapy. Thus, CSFs mobilize the stem cells to enhance the immune process and produce hematopoietic cells such as granulocytes, macrophages in cancer patients. The CSFs resemble hormones that are specifically targeted to produce blood cells in specified regions where the quantity of those cells is low. The CSFs belong to a group of regulatory factors also known as cytokines and does not produce only a single cell type but stimulates colonies of different blood cell types for any specific organ. Hematopoietic cells produced by CSF are step-wise and formation of blast colonies take place initially. Afterwards, the blast cells regenerate and differentiated into multiple progenitor cells consisting of granulocytes, monocytes, macrophages, eosinophills, erythroids, and lymphocytes. The progenitor cells in the granulocyte-macrophage lineage matures into neutrophilic granulocytes and macrophages.
Out of all types of CSF colonies, the Granulocyte-Macrophage (GM-CSF) colony is specially involved in regenerating immune responses in cancer patients. These cytokines stimulates the dendritic cell formation and produces dendritic activity against the cancerous cells. These GM-CSF colonies enhance the immune response of host against melanomas, tumors by reducing their growth and inducing remission. Hence, it can be said that granulocytes and macrophages are infection protective cells and elevates dangerously low levels of white blood cells in cancer patients following chemotherapy. The GM-CSF induction regenerates the bone marrow which is damaged and improves stem cells production.
