The term cell growth is used in the contexts of biological cell development and cell division (reproduction). When used in the context of cell division, it refers to growth of cell populations, where a cell, known as the "mother cell", grows and divides to produce two "daughter cells" (M phase). When used in the context of cell development, the term refers to increase in cytoplasmic and organelle volume (G1 phase), as well as increase in genetic material (G2 phase) following the replication during S phase.[1]
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Cell populations Edit
Cell populations go through a particular type of exponential growth called doubling. Thus, each generation of cells should be twice as numerous as the previous generation. However, the number of generations only gives a maximum figure as not all cells survive in each generation.
Cell size Edit
Cell size is highly variable among organisms, with some algae such as Caulerpa taxifolia being a single cell several meters in length.[2] Plant cells are much larger than animal cells, and protists such as Paramecium can be 330 μm long, while a typical human cell might be 10 μm. How these cells "decide" how big they should be before dividing is an open question. Chemical gradients are known to be partly responsible, and it is hypothesized that mechanical stress detection by cytoskeletal structures is involved. Work on the topic generally requires an organism whose cell cycle is well-characterized.
Yeast cell size regulation Edit
The relationship between cell size and cell division has been extensively studied in yeast. For some cells, there is a mechanism by which cell division is not initiated until a cell has reached a certain size. If the nutrient supply is restricted (after time t = 2 in the diagram, below), and the rate of increase in cell size is slowed, the time period between cell divisions is increased.[3] Yeast cell-size mutants were isolated that begin cell division before reaching a normal/regular size (wee mutants).[4]
Figure 1:Cell cycle and growth
Wee1 protein is a tyrosine kinase that normally phosphorylates the Cdc2 cell cycle regulatory protein (the homolog of CDK1 in humans), a cyclin-dependent kinase, on a tyrosine residue. Cdc2 drives entry into mitosis by phosphorylating a wide range of targets. This covalent modification of the molecular structure of Cdc2 inhibits the enzymatic activity of Cdc2 and prevents cell division. Wee1 acts to keep Cdc2 inactive during early G2 when cells are still small. When cells have reached sufficient size during G2, the phosphatase Cdc25 removes the inhibitory phosphorylation, and thus activates Cdc2 to allow mitotic entry. A balance of Wee1 and Cdc25 activity with changes in cell size is coordinated by the mitotic entry control system. It has been shown in Wee1 mutants, cells with weakened Wee1 activity, that Cdc2 becomes active when the cell is smaller. Thus, mitosis occurs before the yeast reach their normal size. This suggests that cell division may be regulated in part by dilution of Wee1 protein in cells as they grow larger.
Linking Cdr2 to Wee1 Edit
The protein kinase Cdr2 (which negatively regulates Wee1) and the Cdr2-related kinase Cdr1 (which directly phosphorylates and inhibits Wee1 in vitro)[5] are localized to a band of cortical nodes in the middle of interphase cells. After entry into mitosis, cytokinesis factors such as myosin II are recruited to similar nodes; these nodes eventually condense to form the cytokinetic ring.[6] A previously uncharacterized protein, Blt1, was found to colocalize with Cdr2 in the medial interphase nodes. Blt1 knockout cells had increased length at division, which is consistent with a delay in mitotic entry. This finding connects a physical location, a band of cortical nodes, with factors that have been shown to directly regulate mitotic entry, namely Cdr1, Cdr2, and Blt1.
Further experimentation with GFP-tagged proteins and mutant proteins indicates that the medial cortical nodes are formed by the ordered, Cdr2-dependent assembly of multiple interacting proteins during interphase. Cdr2 is at the top of this hierarchy and works upstream of Cdr1 and Blt1.[7] Mitosis is promoted by the negative regulation of Wee1 by Cdr2. It has also been shown that Cdr2 recruits Wee1 to the medial cortical node. The mechanism of this recruitment has yet to be discovered. A Cdr2 kinase mutant, which is able to localize properly despite a loss of function in phosphorylation, disrupts the recruitment of Wee1 to the medial cortex and delays entry into mitosis. Thus, Wee1 localizes with its inhibitory network, which demonstrates that mitosis is controlled through Cdr2-dependent negative regulation of Wee1 at the medial cortical nodes.[7]
Cell polarity factors
Answer:
Cellular membranes or plasma membranes has many functions. Some of these include regulation of cellular transport, and responding to cellular signals or hormones.
<h2>Cellular Transport</h2>
The plasma membrane is made up of the <u>phospholipid bilayer with embedded transmembrane proteins</u>. This makes the cell membrane <u>semi-permeable</u>. Movements of substances depend on the composition of the molecules e.g. glucose and amino acids, as needed by the pancreatic cells. These are larger and uncharged molecules and can't pass freely through the membrane so they utilize the transmembrane proteins via attaching to carrier proteins. This is called <em>passive transport</em>. On the other hand, in <em>active transport</em>, <u>ATP is used</u> to transfer molecules, like Hydrogen, from a low to high electrochemical gradient.
Other kinds of cellular transport are:
- Osmosis and diffusion
- Endocytosis
- Exocytosis
<h2>Cellular Signalling</h2>
The cell membrane is able to signal other neighboring cells by utilizing complex proteins. These proteins may take form as receptors or markers.
<h3>Membrane Receptors</h3>
They act as receivers of extracellular signals and spark intracellular processes. These receive signals from hormones, growth factors, etc.
<h3>
Membrane Markers </h3>
These allow the cells to identify each other and respond if this cell is needs further development as in organ development, or a foreign body to the system.
Answer:<u> Option D
</u>
Solar panels contain a very expensive element, i.e. silicon. This element is able to convert the solar energy into electric energy. The cost of the solar panel gets expensive because of this rare element. It is found in limited areas of the world. That’s why option D is correct. Coal is not used in solar panel, so option B is incorrect. Neither is wind energy, so option A is also incorrect. Water is also not used for exploiting solar energy, which makes option C a wrong answer.
Answer:
1) Sucrose is synthesized in the chloroplast stroma and exported from photosynthetic cells to provide energy and reduced carbon for non photosynthetic plant cells. - FALSE
2) The enzyme rubisco is unusual in that, depending on conditions, it exhibits two different enzymatic activities. - TRUE
3) Ninety percent of the solar energy collected by a photosystem complex is absorbed when photons strike a special pair of chlorophyll molecules at the reaction center of the complex. - FALSE
4) The energy requirement expressed as ATP consumed per molecule of carbon dioxide fixed is higher for a C3 plant than for a C4 plant. - FALSE
5) The ultimate electron donor for the photosynthetic generation of NADPH is always water. - FALSE
