Tay-Sachs disease is a human genetic abnormality caused by insufficient activity of a hydrolytic enzyme called hexosaminidase A.
This results in cells accumulating and becoming clogged with very large and complex lipids. Based on your knowledge of the functions of the various cellular organelles, which organelle must be involved in this condition?
They are spherical sac-like organelles that contain lytic enzymes that destroy aged and unwanted cells. They contain hydrolytic enzymes that destroy GM2, gangliosides a class of glycosphingolipid that are produced by the nerve cells. Mutations in the HEXA gene that leads to the translation of hexosaminidase A causes the genetic abnormality, Tay-Sachs.
A dermatome represents the unilateral area of skin on the body that is innervated by fibers from the sensory portion of a single spinal nerve coming from the spinal cord. Each spinal nerve contains spinal roots (anterior and posterior) that come together to form the spinal nerve.
The central element for all living things is carbon, which is why you might often hear the phrase "carbon-based" lifeforms. Another term is often "organic matter"
