While it is still in the nucleus in order to become a mature mRNA. The mature mRNA is exported from the nucleus to the cytosol, where it is translated at a ribosome to make a polypeptide.
Answer:
4,3,1,5,2
4. Vesicles full of acetylcholine are stored at the axon terminal.
3. Action potential arrives at the neuromuscular junction.
1. Action potential is propagated in the sarcolemma.
5. Acetylcholine is released into the synaptic cleft.
2. Acetylcholine binds to ligand gated sodium channels.
Explanation:
Nerve impulse is generated from somatic motor neurons and reaches neuromuscular junction. The nerve impulse specifically reaches a region named 'synaptic end bulbs' at axon terminal. These synaptic end bulbs are in turn connected to the motor end plate region of a sarcolemma.
As soon as the nerve impulse reaches neuromuscular junction, it triggers the opening of voltage gated ion channels which in turn facilitate the influx of Ca²⁺ from the extracellular fluid to the inside of neuron where synaptic vesicles containing neurotransmitter acetylcholine are already stored.
The Ca²⁺ causes the exocytosis of synaptic vesicles which fuse with the plasma membrane of motor neuron as a result of which acetylcholine is released in the synaptic cleft.
The acetylcholine further binds with the acetylcholine receptor which is present at the motor end plate of a skeletal muscle fibre. These receptors are ligand gated ion channels.
Binding of acetylcholine with its receptor causes the ion channels to open and cations like Na⁺ enter the muscle fibre so as to make the electric potential inside the muscle positive.
therapy would be the missing word because of the kind of cancer he has.
Paraphrasing is the act of rewording, revising, simplifying and expressing the text in your own words with additional clarity. Note that condensing the text to a shorter form should not be in your interests because that would be summarizing, not paraphrasing. Check this out:
Nonliving organisms and lifeless organisms are not the same thing. Inanimate organisms are not dead, they're nonliving. Being nonliving means not having a characteristic of life, it means that the object is inorganic. A valid example could be a rock. A rock has never had a characteristic of life. Being deceased means that life once inhabited the being and has left it. Just as a moose gains life from conception, it's deemed dead once life has left it. In science, nonliving organisms and lifeless organisms are not the same thing; one was gifted life and one was inanimate from the beginning.
(Professional enough?) c;
