The answer is evolutionary!
I hope I was able to help. :)
There are numerous circumstances that give pathogens the chance to harm people.
The first occurs when an infection has already weakened the immune system. In situations like this, other pathogens may infect the host opportunistically and cause an infection. If the human host does not maintain proper personal and environmental hygiene, that is another condition. Many pathogens thrive in unclean environments, so by failing to maintain proper environmental hygiene, a person increases his risk of contracting a pathogen.
Finally, since so many pathogens are transferred by vectors, humans are more likely to contract the diseases that these vectors aid in spreading if they do not take the necessary precautions to stop their activity.
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Skin color would be a good indicator...
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