Question

The ability of vibrio cholerae to cause disease depends on a number of factors. What are general requirements for any organism to cause disease within a host?

Answer 1

Disease

Explanation:

• Pathogenicity is the ability to produce disease in a host organism
• Microbes express their pathogenicity by means of their virulence, a term which refers to the degree of pathogenicity of the microbe
• The relationship between a host and a pathogen is dynamic, since each modifies the activities and functions of the other
• The outcome of such a relationship depends on the virulence of the pathogen and the relative degree of resistance or susceptibility of the host, due mainly to the effectiveness of the host defense mechanisms
• Hence, general requirements for any organism to cause disease within a host are: evasion of host defenses , gaining access to the host via a portal of entry, adherence to host tissues