How does a circular template stop replication a. A polymerase falls off at the correct time, different polymerases last differen
t amounts of time b. Short 23bp sequences called ter sites recognized by the Tus protein that stops replicaton c. The oriC site is recognized by the Tus protein that terminates replication d. Termination occurs when the supply of nucleotides is depleted
For termination to occur in a circular template replication, the use of termination sequences (Ter sites) in complex with the Tus protein is adopted. These ter sites have polarity arresting the replication forks precisely at the ter sites if the forks are in orientation to the oriC. It aid in efficiently in trapping the replication forks allowing them to meet within a specific region on the chromosome. The tus protein may also act to stop some replicative helicases and RNA polymerases.
