The hypothesis by Coleman was that the product of the ob+ gene was the appetite suppressing hormone. Hence, the homozygous ob/ob mutant are in a position to synthesize that hormone, and its circulating level would be zero. He also hypothesized that the product of the db+ gene was the receptor for the appetite-suppressing hormone. Thus, the homozygous db/db mutant would be able to synthesize the hormone but would not be in a position to respond to it. It would eat excessively and produce large amounts of body fat, which in turn would produce large amounts of appetite-suppressing hormone . In the absence of a receptor, the db/db mutant's hormone level would remain abnormally high.
Coleman's hypothesis were confirmed when the precise functions of the ob+ and db+ genes were determined. The peptide hormone encoded by the ob+ gene was named Leptin.
Answer:
The waste would be digested by the lysosomes and transported out of the cell by probably diffusion but from what I know, they would be recycled.
Explanation:
Answer:
B. The <em>pituitary</em> gland
Explanation:
Can't be the ovaries, they're down by the hips!
Can't be adrenal glands, they're on top of the kidneys!
Can't be the thyroid, that's low on the front of the neck or something like that!
It's B, the pituitary; it's on the base of the brain.
Have a great day!
It gets passed onto the baby
