Answer:
Frameshift mutations change the entire protein sequence and messes up the entire amino acid sequence that occurs after mutations, but substitution only changes one single amino acid.
Answer:
I believe the answer you are looking for is the Lithosphere
The answer is: An air conditioner that turns on if the temperature gets too hot.
Even though they hurt you emotionally, Negative feedbacks serve their own important function. They keep your feet on the ground and prevent you from getting too arrogant.
This function is similar as a cooling air conditioner. Hot temperature in the comparison above represent your arrogance and the air conditioner represent the negative feedback.
