Disruption of axonal transport would be a good target for his drug.
<h3>What is disruption of axonal transport?</h3>
- Axonal transport defects are among the early molecular events leading to neurodegeneration in mouse models of amyotrophic lateral sclerosis (ALS).
- Gene expression profiles indicate that dynactin-1 mRNA is downregulated in degenerating spinal motor neurons of autopsied patients with sporadic ALS.
- Disruption of axonal transport also underlies the pathogenesis of spinal muscular atrophy and hereditary spastic paraplegias.
- The neurotoxin β,β′-iminodipropionitrile (IDPN) selectively disrupts slow axonal transport without affecting fast anterograde or retrograde axonal transport.
- Impairment of slow axonal transport causes a proximal accumulation of neurofilaments.
- Because neurofilaments regulate axonal diameter, this accumulation leads to a marked swelling of the axon.
- Acrylamide causes decreased axonal transport, also causing proximal accumulations of neurofilaments and swelling.
To learn more about axonal transport,
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Answer:
how are we supposed to know how many we read today?
Explanation:
because not many people count how many words they have each week.
Anaphylaxis is <span>a severe systemic allergic reaction characterized by bronchoconstriction, hypotension, and shock.</span>
<span>
with more atmospheric carbon dioxide to convert to plant matter in photosynthesis, place able to grow more. Photosynthesis has no negative effect on Carbon Cycle. Carbon Cycle has a negative effect on photosynthesis.
More Carbon dioxide is not necessarily needed in Photosynthesis. </span>
Answer:
It’s A,B,E!!
Explanation:
I just did it on USATestPrep!!
