1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
zimovet [89]
3 years ago
14

A variation of the acetamidomalonate synthesis can be used to synthesize serine. The process involves the following steps: Ethox

ide ion deprotonates diethyl acetamidomalonate, forming enolate anion 1; Enolate anion 1 makes a nucleophilic attack on formaldehyde, forming tetrahedral intermediate 2; Protonation of the oxyanion forms alcohol 3; Acid hydrolysis yields dicarboxyamino alcohol 4; Decarboxylation leads to the final amino acid. Write out the mechanism on a separate sheet of paper, and then draw the structure of dicarboxyamino alcohol 4.

Chemistry
1 answer:
Alex73 [517]3 years ago
5 0

Answer:

See detailed mechanism in the image attached

Explanation:

The mechanism shown in detail below is the synthesis of serine in steps.

The first step is the attack of the ethoxide ion base on the diethyl acetamidomalonate substrate giving the enolate and formaldehyde.

The second step is the protonation of the oxyanion from (1) above to form an alcohol as shown.

Acid hydrolysis of the alcohol formed in (3) above yields a tetrahedral intermediate, a dicarboxyamino alcohol.

Decarboxylation of this dicarboxyamino alcohol yields serine, the final product as shown in the image attached.

You might be interested in
A 51.24-g sample of Ba(OH)2 is dissolved in enough water to make 1.20 liters of solution. How many mL of this solution must be d
g100num [7]

Answer:

0.40 L

Explanation:

Calculation of the moles of Ba(OH)_2 as:-

Mass = 51.24 g

Molar mass of Ba(OH)_2 = 171.34 g/mol

The formula for the calculation of moles is shown below:

moles = \frac{Mass\ taken}{Molar\ mass}

Thus,

Moles= \frac{51.24\ g}{171.34\ g/mol}

Moles= 0.2991\ mol

Volume = 1.20 L

The expression for the molarity is:

Molarity=\frac{Moles\ of\ solute}{Volume\ of\ the\ solution}

Molarity=\frac{0.2991\ mol}{1.20\ L}=0.24925\ M

Thus,

Considering

Molarity_{working\ solution}\times Volume_{working\ solution}=Molarity_{stock\ solution}\times Volume_{stock\ solution}

Given  that:

Molarity_{working\ solution}=0.100\ M

Volume_{working\ solution}=1\ L

Volume_{stock\ solution}=?

Molarity_{stock\ solution}=0.24925\ M

So,  

0.100\ M\times 1\ L=0.24925\ M\times Volume_{stock\ solution}

Volume_{stock\ solution}=\frac{0.100\times 1}{0.24925}\ L=0.40\ L

<u>The volume of 0.24925M stock solution added = 0.40 L </u>

6 0
3 years ago
Summarize: Complete the following statements:
egoroff_w [7]

Answer:

Explanation:

Taking into account the definition of Avogadro's Number, the correct answers are:

1 mole of any element contains 6.023×10²³ atoms

1 mole of any compound contains 6.023×10²³ molecules

You have to know that Avogadro's Number or Avogadro's Constant is called the number of particles that make up a substance (usually atoms or molecules) and that can be found in the amount of one mole of said substance. Its value is 6.023×10²³ particles per mole.

Avogadro's number represents a quantity without an associated physical dimension, so it is considered a pure number that allows describing a physical characteristic without an explicit dimension or unit of expression.

Avogadro's number applies to any substance, because the number of elementary units in a mole of a substance is, by definition, a  constant that does not depend on the material or the type of particle considered.

So, in this case, the correct answers are:

1 mole of any element contains 6.023×10²³ atoms

1 mole of any compound contains 6.023×10²³ molecules

hope that help you mark me as brinilylist pls

4 0
2 years ago
Which separation techniques will you apply for the separation of the following? a) oil from water b) kerosene and petrol c) salt
REY [17]

Answer:

A) Separating funnel method

B) Simple Distillation

C) Evaporation

D) Sublimation

E) It is based on the principle of separation whereby even though two substances are dissolved in the same solvent, their respective solubilities could be different. Thus, the component that has more solubility will rise fastest and will therefore get separated from the mixture.

Explanation:

A)

B) Kerosene and petrol are both miscible liquids and the difference in their boiling point temperature is not more than 25°C. Thus, we make use of Simple distillation.

C) Can be separated by evaporation where the water is boiled and it evaporates and leaves the salt behind

D) To separate camphor from salt, we use sublimation so the camphor can change directly from solid to the gas state without passing through the liquid state.

E) Chromatography is used to separate components of a mixture.

It is based on the principle of separation whereby even though two substances are dissolved in the same solvent, their respective solubilities could be different. Thus, the component that has more solubility will rise fastest and will therefore get separated from the mixture.

7 0
3 years ago
How much of a 3.75 M KI solution would you need to prepare 252.5 mL of a 0.780 M KI solution?
saveliy_v [14]
Answer: 52.5 mL

Hope this helps!
4 0
2 years ago
Intravenous saline solutions are often administered to patients in the hospital. Normal saline solution containers has a concent
zalisa [80]

0.02 mol NaCl

Explanation:

(0.2M NaCl)×(0.10 L) = 0.02 mol NaCl

8 0
3 years ago
Other questions:
  • Why does water flow decrease in your shower when someone flushes the toilet ​
    11·2 answers
  • -<br> __C6H1206 → <br> __C + __H2 +<br> __O2<br> Balance equation
    11·1 answer
  • 80.0 liters of oxygen gas is collected over water at 50 degrees celcius. the atomsphereic pressure in the room is 96.00 kPA. wha
    14·1 answer
  • What are the particles of solid,liquid,and gas
    10·1 answer
  • Într-un amestec de „x” molecule de hidroxid de amoniu NH4OH și 7 molecule de apă se găsesc 39 atomi de hidrogen. Valoarea lui „x
    5·1 answer
  • What is the hydrogen ion concentration of a substance with a hydroxide ion concentration of 1.07x10-10M?
    8·1 answer
  • What is the name of Hg2O
    6·2 answers
  • What are the SI units for specific heat capacity
    9·2 answers
  • PLEASE HELP DUE IN 30 MINUTES NO LINKS PLEASE ​
    15·1 answer
  • Which of the following is a pure substance?
    15·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!