A variation of the acetamidomalonate synthesis can be used to synthesize serine. The process involves the following steps: Ethox
ide ion deprotonates diethyl acetamidomalonate, forming enolate anion 1; Enolate anion 1 makes a nucleophilic attack on formaldehyde, forming tetrahedral intermediate 2; Protonation of the oxyanion forms alcohol 3; Acid hydrolysis yields dicarboxyamino alcohol 4; Decarboxylation leads to the final amino acid. Write out the mechanism on a separate sheet of paper, and then draw the structure of dicarboxyamino alcohol 4.
1 answer:
Answer:
See detailed mechanism in the image attached
Explanation:
The mechanism shown in detail below is the synthesis of serine in steps.
The first step is the attack of the ethoxide ion base on the diethyl acetamidomalonate substrate giving the enolate and formaldehyde.
The second step is the protonation of the oxyanion from (1) above to form an alcohol as shown.
Acid hydrolysis of the alcohol formed in (3) above yields a tetrahedral intermediate, a dicarboxyamino alcohol.
Decarboxylation of this dicarboxyamino alcohol yields serine, the final product as shown in the image attached.
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Answer:
moles of glucose
<u>2.3166 moles of glucose</u>
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Explanation:
The balance reaction for the formation of glucose is :
here , CO2 = carbon dioxide
H2O = water
C6H12O6 = glucose
O2 = Oxygen
According to this equation :
6 mole of CO2 = 6 mole of H2O = 1 mole of C6H12O6 = 6 mole of O2
We are asked to calculate the mole of Glucose from carbon dioxide.
So,
6 mole of CO2 produce = 1 mole of C6H12O6
1 mole of CO2 will produce =
moles of glucose
13.9 moles of CO2 will produce :
=2.3166 moles of glucose
Note : first , Always calculate for one mole (By dividing)
. After this , multiply the answer with the moles given.
Always write the substance whose amount is asked(glucose) to the right hand side