1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
zimovet [89]
3 years ago
14

A variation of the acetamidomalonate synthesis can be used to synthesize serine. The process involves the following steps: Ethox

ide ion deprotonates diethyl acetamidomalonate, forming enolate anion 1; Enolate anion 1 makes a nucleophilic attack on formaldehyde, forming tetrahedral intermediate 2; Protonation of the oxyanion forms alcohol 3; Acid hydrolysis yields dicarboxyamino alcohol 4; Decarboxylation leads to the final amino acid. Write out the mechanism on a separate sheet of paper, and then draw the structure of dicarboxyamino alcohol 4.

Chemistry
1 answer:
Alex73 [517]3 years ago
5 0

Answer:

See detailed mechanism in the image attached

Explanation:

The mechanism shown in detail below is the synthesis of serine in steps.

The first step is the attack of the ethoxide ion base on the diethyl acetamidomalonate substrate giving the enolate and formaldehyde.

The second step is the protonation of the oxyanion from (1) above to form an alcohol as shown.

Acid hydrolysis of the alcohol formed in (3) above yields a tetrahedral intermediate, a dicarboxyamino alcohol.

Decarboxylation of this dicarboxyamino alcohol yields serine, the final product as shown in the image attached.

You might be interested in
Help science loook at pictureeee
Blizzard [7]

Answer:  Convection current

Explanation:

8 0
3 years ago
Read 2 more answers
How many atoms are in each compound ?
noname [10]
Compounds are made of two or more atoms of different elements, such as water (H2O) and methane (CH4). Atoms are not drawn to scale. Molecules of compounds have atoms of two or more different elements.
7 0
3 years ago
Given two temperatures, 36 °F and 72 °F, which of the following correctly compares the number of opportunities for particles to
Liono4ka [1.6K]

The correct answer is "Greater at 72 °F " hope it helps

5 0
3 years ago
GIVING ALOTS OF POINTS !!! Is the following sentence true or false? Where a river flows in a straight
Neko [114]

Answer: yes true

Explanation: 1. Toward the middle of a river, water tends to flow fastest; toward the margins of the river it tends to flow slowest. 2. In a meandering river, water will tend to flow fastest along the outside bend of a meander, and slowest on the inside bend.

6 0
2 years ago
What orbital is represented by the transition metals in period four
andreev551 [17]

The name transition metal refers to the position in the periodic table of elements. The transition elements represent the successive addition of electrons to the d atomic orbitals of the atoms. In this way, the transition metals represent the transition between group 2 (2A) elements and group 13 (3A) elements.

8 0
3 years ago
Other questions:
  • Why does the magnet disolves when is insert in hydrochloric acid
    6·1 answer
  • Complete each nuclear fusion reaction.
    11·2 answers
  • What type of bonding is found in the molecule HBr?
    10·1 answer
  • An empty water bottle is full of air at 15°C and standard pressure. The volume of the bottle is 0.500 liter. How many moles of a
    6·1 answer
  • The graph shows the volume of a gaseous product formed during two trials of a reaction. A different concentration of reactant wa
    10·1 answer
  • I NEED HELP PLEASE, THANKS! BRAINLIEST :)
    11·1 answer
  • Which of the following is the best indication that a chemical change has taken place?
    15·2 answers
  • Is Ba(OH)2 a interpolate or extrapolate? ​
    14·1 answer
  • Which is not an example of a
    6·1 answer
  • Given the nuclear equation below, this equation is an example of
    15·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!