Hepatocyte growth factor (HGF) is the only known growth factor that activates quiescent satellite cells in skeletal muscle.
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin.
HGF, produced by some cancer cells, stimulates c-Met, through activation of the autocrine signaling system. Hepatocyte growth factor (HGF) is a paracrine hormone that plays an important role in epithelial-mesenchymal transition. HGF secreted by mesenchymal cells affects many properties of epithelial cells, such as proliferation, motility, and morphology.
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Answer:
Domain is the highest level of classification.
Hitchhicker's thumb is a condition in which a person is able to bend his thumb backwards. This trait can be seen in many people but the condition is recessive, which means a person needs two alleles for hitchhiker's thumb to have this particular characteristics. The gene for straight thumb is commonly indicated by T while that for hitch hicker's thumb is indicated by t.
Let's see what will happen if a person heterozygous for hitchhiker's thumb marries a woman who is also heterozygous for hitchhiker's thumb.
P1: Tt X Tt
Gametes: t T : t T
Offsping : TT : Tt : tT : tt
TT : 25 % : Straight thumb
Tt + tT : 50% : Straight thumb
tt : 25% : Hitch hicker's thumb
Therefore, there are 25 % chances that their offspring will have Hitch hicker's thumb and 75 % chances that they will have straight thumb.
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