The substrate and the active site both need to fit together perfectly in order for the enzyme to work properly. If their shape is changed, typically through heat or a change in pH, the enzyme will not work.
Answer: Cushing Syndrome
Explanation:
Cushing Syndrome occurs when the body is exposed to high level of cortisol for a long time either externally (taken into the body from outside ) or internally (secretion in excess of the hormone called cortisol by the body) . It can also be called hypercortisolism .
The symptoms of Cushin Syndrome may vary depending on the severity of the excess cortisol secretion. Females may have irregular menstrual period due to this condition.
Asthma and arthritis patients who take corticosteroids and experiences the mentioned symptoms should seek medical attention for diagnosis.
Both black holes and neutron stars are corpses of stars that died in catastrophic explosions known as supernovas, outbursts that can make a star briefly outshine all of the other stars in its galaxy. When a star goes supernova, the core of its remains collapses under the strength of its own gravitational pull.
I think it is A but i am not sure
