This varies from person to person. There is a point in time at which hormones in a persons body begin to loose their effective functions, a period I have heard reffered to as adult puberty. In women this is marked by menopause. While you can still theoretically maintain a healthy body at this time, it becomes increasingly difficult. Maintaining a healthy diet and constant exercise are essential to achieving this. A doctor won't tell you much more than this.
C. Lung Cancer
Lung Cancer kills 9,200 people in the United States every year.
Blood pressure, exercise, emotional states (such as stress), body size, and caffeine all affect heart rate.