Most TP53 mutations change single amino acids in the p53 protein, which leads to the production of an altered version of the protein that cannot control cell proliferation and is unable to trigger apoptosis in cells with mutated or damaged DNA. As a result, DNA damage can accumulate in cells
Well Primary Succession means you are the first organisms of that area after it is destroyed completely or if it's new. Secondary Succession is when an area is not destroyed completely but the organisms that remain colonize the area again. I believe it's C.