Question

Bob has a genetic condition that affects his skin Bob's wife, Eleanor, has normal skin. No one in Eleanor's family has ever had the skin condition Of their eleven children, all six sons have normal skin, all five daughters have the same skin condition as Bob. Based on Bob and Eleanor's family history, what inheritance pattern does the skin condition most likely follow?
a. autosomal dominant.
b. X-linked dominant.
c. Y-linked dominant.
d. autosomal recessive.
e. X-linked recessive Affected Unaffected

Answer 1

Answer:

The correct answer is b. X-linked dominant.

Explanation:

In X- linked dominant disease the disease is linked with the X chromosome which shows its effect in the phenotype when transferred from the affected parent. Bob is affected by this X- linked dominant skin disease which means he will transfer this disease to all his daughters because in daughter one X chromosome comes from father and one from mother.  

Therefore all girls will have X- linked dominant trait of skin disease and will show the same skin condition as bob but all males would be normal as the Y chromosome will be transferred to them from father and normal X chromosome will come from mother.