Answer : The dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation :
The expression for reversible competitive inhibition when apparent Km affected by addition of the inhibitor is:
![K_m_a=K_m[1+\frac{I}{K_i}]](https://tex.z-dn.net/?f=K_m_a%3DK_m%5B1%2B%5Cfrac%7BI%7D%7BK_i%7D%5D)
where,
= apparent value = 52 µM
= Michaelis–Menten constant = 40 µM
I = inhibitor concentration = 1.5 µM
= dissociation constant of the PFK‑inhibitor complex
Now put all the given values in the above formula, we get:
![52\mu M=40\mu M[1+\frac{1.5\mu M}{K_i}]](https://tex.z-dn.net/?f=52%5Cmu%20M%3D40%5Cmu%20M%5B1%2B%5Cfrac%7B1.5%5Cmu%20M%7D%7BK_i%7D%5D)
Therefore, the dissociation constant of the PFK‑inhibitor complex is, 5 µM
The correct option is GOLGI VESICLES.
Golgi vesicle is a transporting structure that is found in the Golgi apparatus. The principal function of Golgi vesicle is to transport packaged proteins to their different locations within the cell.
These microbial infections that are acquired by hospital patients as they are being used as the compromised host are the nosocomial infections. These type of infections are primarily caused by bacterial pathogens entering the patient's body and mainly causes urinary tract infection, pneumonia, and other illnesses.
