I'd go with B because it makes sense to me.
Answer:
Water and temperature
Explanation:
Water and temperature are the two most important factors that regulate the distribution of organisms in terrestrial habitats. Water is required for survival by living beings. The availability of water is limited in many habitats such as desert habitats. In such land habitats with water scarcity, the organisms adapted to withstand the limited water availability are found.
Likewise, temperature also affects the distribution of organisms in terrestrial habitats. The presence of temperature conditions below and above the tolerance range of the organisms restricts their geographical distribution. Temperature regulates the enzyme kinetics. Metabolic pathways are catalyzed by enzymes that function under optimal temperature conditions only. Water serves as a medium for metabolic reactions and also regulates body temperature.
Cancer is unchecked cell growth. Mutations in genes can cause cancer by accelerating cell division rates or inhibiting normal controls on the system, such as cell cycle arrest or programmed cell death. As a mass of cancerous cells grows, it can develop into a tumor
