The lower the level of the pyramid, the more important the needs are. On the most bottom part, you will see physiological needs such as the need for food and water, for shelter and for warmth, while higher up at the top you'll see things such as being esteemed as someone great or being successful at what you do. Those thing are higher because they rare less important for us than physiological needs.
Heart disease and obesity.
After graduating, Einstein faced major challenges in terms of finding academic positions, having alienated some professors over not attending class more regularly in lieu of studying independently. Hope this helps !