Question

p53 is a protein that functions to block the cell cycle if DNA is damaged. If the damage is severe this protein can cause cell death. If there is a mutation in the p53 protein, we might expect what to happen?

Answer 1

Answer:

If there is a mutation in the p53 protein then this leads to abnormal cell growth and cell death or apoptosis does not occur.

Explanation:

p53 is a tumor supressor protein.p53 is encoded by TP53 gene.The protein is named so because the protein has a molecular weight of 53 kilo Dalton and this protein helps in programmed cell death or apoptosis.

               The mutation in p53 result in the abnormal cell growth due to accumulation of mutated p53 protein, an important sign of development of cancer.