1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Anarel [89]
2 years ago
14

If you treated embryos with a Notch inhibitor how would this affect the specification of venous and arterial endothelial cells?

Biology
1 answer:
Alisiya [41]2 years ago
4 0

Answer:

d. all endothelial cells would be venous

Explanation:

The Notch signaling pathway is a cell signaling system which consist basically of 4 NOTCH genes ( NOTCH1, NOTCH2, NOTCH3, and NOTCH4) each of them having the information to build a particular cell membrane receptor protein.

It has been demonstrated in zebrafish embryos that Notch signaling are highly determinant factors during vascular development, and a key function of these genes was specifically to regulate the differentiation of arterial fate in endothelial cells.

Notch signaling-deficient embryos showed a loss of expression of arterial markers such as ephrinB2 from arterial vessels with an accompanying expansion of venous markers into normally arterial domains. In contrast, embryos in which Notch signaling had been ectopically activated, meaning an activation out of "proper" place (where not expected, e.g. venous endothelial), exhibited the contrary phenotype, this is a suppression of vein-specific markers with ectopic expression of arterial markers in venous vessels.

To summarize, when Notch is supressed (in this case inhibited with a specific Notch inhibitor) arterial fate of endothelium is not followed, and venous fate is stablished. Thus, endothelial cells (those expected to form venous tissues but also arterial ones) would specified as venous.  

You might be interested in
When the Bicoid protein is expressed in Drosophila, divisions between cells in the embryo are not yet fully developed. This info
AleksAgata [21]

When the Bicoid protein is expressed in Drosophila, divisions between cells in the embryo are not yet fully developed. This helps to explain that (B) Bicoid protein diffuses throughout the embryo in a concentration gradient.

Bicoid protein acts as a morphogen. This means it shows its effect when the concentration gradient is high. Also abbreviated as Bcd, the protein helps in establishing the anterior and posterior region of the Drosophila. It also represses the translation of caudal mRNA.

Embryo is the initial stage of a microorganism, right after the fertilization. In vertebrates, this stage does not last much longer because the development of organs begins.

To know more about bicoid protein, here

brainly.com/question/13063204

#SPJ4

7 0
2 years ago
Harry notices that one of his houseplants does not grow very well compared to his other houseplants. He asks himself “What is di
Fed [463]

Answer:

The correct option is D. When Harry asks “What is different with this plant that does not grow very well compared with the other house plants?”

Explanation:

A scientific method can be described as a method on the basis of which all scientific theories or researches are made. A scientific method begins with a question. A hypothesis is made in response to the question. To test the hypothesis, experimentation is done. And finally a hypothesis is considered true or false on the basis of experiments made.

In the question above, Harry's problem is described in the question which he makes. And then he derives a possible hypothesis for his question.

8 0
3 years ago
Based on the diagram below, what type of organism is the crown-of-thorns sea star?
igor_vitrenko [27]

Predator


http://fortnitepranaholistico.com/

4 0
3 years ago
What is homolog?<br><br><br> PLEASE ANSWER
MAXImum [283]

Explanation:

A gene similar in structure and evolutionary origin to a gene in another species. if it's wrong let me know so I'll look into more detail.

7 0
2 years ago
Which statement is most likkely to applyto a cell that has DNA whitin its ytoplasm
Harman [31]

Answer:

It performs all functions for the organisms

7 0
3 years ago
Other questions:
  • what happens when a cell is subjected to a solution where the water concentration is equal to that inside a cell?(isotonic solut
    8·1 answer
  • Which term refers to an organism that eats prey?
    15·1 answer
  • Explain the structure of the DNA molecule. In your answer include the parts that make up the molecule, how these parts
    9·2 answers
  • Which is not true of lipids
    5·2 answers
  • Which type of plant makes up the largest group in the Plantae kingdom?
    8·1 answer
  • Animals, like other life-forms, evolved in the ocean. What made water a better nursery than land for the evolution of animals?​
    8·2 answers
  • How does the temperature change throughout the cycle on an average star?​
    8·1 answer
  • What general name is given to tracts that connect the right and left cerebral hemispheres?
    8·1 answer
  • Why is it important for the brain to be so well protected?
    13·1 answer
  • Which layer of the stomach produces digestive juices?
    9·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!