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Ann [662]
3 years ago
14

Bodybuilders that take anabolic steroids such as androstenedione and testosterone often suffer from gynecomasty (enlarged breast

s) as a side effect. Knowing that in women breast growth is stimulated by estrogens, explain why this happens to bodybuilders. The law of mass action also applies here! Again, make sure to mention the substrate and product of the reaction.
Medicine
1 answer:
Whitepunk [10]3 years ago
8 0

Answer:

Gynaecomastia occurs due to

1) Feedback inhibition of pituitary.

2) Conversion of exogenous androgens into estrogen (aromatization)

Substrate : Androgen

Product : Estradiol ( estrogen )

Enzyme involved : Aromatase

Explanation:

Gynaecomastia is a condition in which the mammary

glands, or breasts, enlarge and become sore and

tender to touch. It is due to the chemical change

in testosterone brought about by a process called

aromatisation, when the male hormone is converted

to a form of estrogen, the female sex hormone.

There is initially a sore feeling in the breast. A

skin ridge appears on the outer side of the areola

together with a halo appearance around the area

but no swelling. As the course continues, a swelling

develops and it becomes tender. Fatty tissue

builds up around the area and the breast becomes

prominent. At times there may be a secretion of

fluid from the nipple when it is squeezed. Steroids

should be stopped. If recovery does not occur by

the end of 2 months, surgery should be considered.

Other causes of gynaecomastia that may need to

be considered are the use of medications such as

Tagamet, a treatment for gastric problems, HCG and

spironolactone. Some body builders use this latter

drug to reduce body fluid. Occasionally boys in the

post-pubertal phase develop breast enlargement due

to endocrine imbalance totally unrelated to steroids.

Gynaecomastia also occurs as a result of feedback inhibition of the pituitary.

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Who discovered dengue fever
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In 1943, Ren Kimura and Susumu Hotta first isolated the dengue virus. These two scientists were studying blood samples of patients taken during the 1943 dengue epidemic in Nagasaki, Japan.

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2 years ago
What are the phases of mitosis and what happens in each?
xxMikexx [17]

Explanation:

Mitosis is the nuclear division followed by cytokinesis, which leads to the production of two daughter cells.

<u>It includes the following phases - </u>

1. Interphase - In this process the Cell actively metabolizes and prepare itself for the process of mitosis and the Chromosomes are not clearly discerned .

2. Prophase - In this phase , the Chromatin gets to condense and can be visualized under a light microscope and  Nucleolus gets disappeared , Centrioles begins to move to opposite ends of the cell .

3. Metaphase - In this phase the Spindle fibers gets align the chromosome along the middle of the nucleus of the cell thereby creating a metaphase plate .

4. Anaphase - In this phase , the chromosomes which got paired up gets separate at the kinetochores and move to the opposite directions of the cell , the Spindle microtubules and physical interaction among polar microtubules is responsible for kinetochore movement.

5. Telophase - In this phase , the Chromatids completely move to the opposite poles of the cell , and new membranes start forming around the daughter nuclei and the Chromosomes disperse and become invisible. Cytokinesis starts.

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4 0
3 years ago
What is an adjective​
qaws [65]

Answer:

A word or phrase naming an attribute, added to or grammatically related to a noun to modify or describe it.

Explanation:

Examples are: beautiful, pretty, heavy.

Any descriptive words are adjectives.

Example Sentence: That is a thick noodle.

Thick is the adjective because it is adding description to the noun, which is noodle.

Hope this helps! Feel free to ask questions!

7 0
2 years ago
Whether someone with a diathesis develops the disorder is determined by
stepan [7]

Answer:

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Explanation:

From the perspective of the diathesis-stress model, a disorder is the result of the interaction between a genetic predisposition or vulnerability (diathesis), with external factors or personal experiences (stress). This model is used to explain the development of mental disorders with a clear genetic basis, such as schizophrenia, bipolar disorder, etc. The appearance of the disorder will depend on the combination of both factors. The more genetic predisposition you are, the more likely you are to develop these low-stress diseases. And on the contrary, a low predisposition protects us from suffering a mental disorder, even if different stressors occur in our life.

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To know more about inflammation, here

brainly.com/question/15380302

#SPJ1

3 0
11 months ago
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