The noble gases already have a full outer shell. The noble gases break the trend by being less reactive than the elements to their left.
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DNA is synthesized in the middle part of Interphase, which is usually denoted S in the series G1 - S - G2 </span><span>"There are 3 stages of interphase: G1 in which the cell grows and functions normally. Once it grows too large it enters the synthesis (S) phase. In S phase the cell makes exact copies of its DNA. It is now ready for G2 phase where it makes sure all of its chromosomes and organelles are ready for mitosis."</span>
I have searched everywhere, but I have not found the proposals of the question, but I will explain to you what is the endoplasmic reticulum so that you can answer it.
The endoplasmic reticulum is a eukaryotic organelle located in the cytoplasm.
The endoplasmic reticulum is a network of membrane tubules (often interconnected) scattered throughout the cytoplasm of eukaryotic cells. Its membrane, which alone represents more than half of the cellular membrane system, is in contact with the nuclear envelope.
The endoplasmic reticulum can be:
Granular (or rough) (RER) that is to say associated with ribosomes.
Smooth (SER).
The granular endoplasmic reticulum is the place of synthesis (in the associated ribosomes) of the proteins secreted outside the cell and of the proteins and lipids constituting the membranes of the cellular organelles. Golgi, lysosomes, mitochondria, nucleus, ribosomes, vesicles ...). It participates in the correct folding of the proteins that have just been synthesized.
The smooth endoplasmic reticulum participates in cellular metabolism, synthesizing lipids and storing calcium.