Answer:
Firstly, what plague? Are we talking about the Bubonic plague?
Explanation:
1) By rats, Which served as the vector which spread the disease.
2) Lack of hygiene and them throwing their sewage and was out of their window into the street.
The colonial policies and practices that played a part in peaceful or violent transitions to self-rule were very complex. One major one which had a very important role here was Apartheid. This was an important policy which had at its core racial segregation between black and white people.
The catholic church would usually sentence any who proved them wrong with science to death because the church was the government
The southern colonies (and the colonies in the Caribbeans) required slave labor and indentured servants to maintain plantations that grew valuable crops such as sugar canes and tobacco. Harvesting these crops were often labor intensive that many free workers were unwilling to do without high wages that plantation owners did not wish to pay. These crops could only be grown in the south (or the Caribbean) due to the soil and climate.
Japan needed new territory because of over population.